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Pharmacology

BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease

John, V
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BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease

Product Description

BACE (Beta-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery. By enhancing the reader's understanding of the various aspects of the BACE drug-discovery process, this much-needed reference will serve as a key resource for all scientists involved in Alzheimer's research--and inspire new approaches to treatment of AD.

ISBN 9780470293423Edition 01Binding Cloth